Product Description
In the development of eNOXIDE, the MuscleMeds research team undertook a massive review and evaluation of the Nitric Oxide (NO) precursor and stimulating products on the market and numerous
Nitric Oxide research studies to determine the best way for boosting
NO levels. After extensive review, MuscleMeds scientists discovered that the NO precursor and NO stimulating products were at best minimally effective in elevating NO in the bloodstream, with individual effectiveness results varying. A plethora of research indicates the dose-response limitations of using orally administered arginine or other arginine based compounds, such as Arginine, Arginine Alpha-Ketoglutarate (AAKG), Citrulline and other NO precursors and stimulators. For example, when reviewing the research conducted using arginine, it was found that in order to achieve some elevation of NO, very large dosages of arginine were required, using intravenous administration. Even more problematic, the research reveals that the oral dosage methods used by all supplements (capsules, tablets, powder mixes, liquid drinks, etc.) were much less effective compared to intravenous (I.V.) administration.
Other efficacy concerns related to using NO precursors and NO stimulators include the widespread practice of products containing low, ineffective dosages. For example, a typical effective dosage reported in the medical research report is 30 grams of arginine, administered intravenously (I.V.) all within 30 minutes. Compare this to the low,
sub-optimum dosing common among most NO supplements, where
3 grams or less of Arginine or AAKG is administered. To make matters worse, in an effort to prolong the NO elevations many of these products make the mistake of using a 6-hour sustained release tablets. Sustaining a sub-optimal 3 gram dose over a 6-hour period translates into delivering an even more ineffective sub-optimal dosage of a mere
0.5 grams per hour. Moreover, factor in that oral arginine is estimated to be about 70% bioavailable by some experts, and your dosage becomes even more dismal and sub-optimal (0.35 grams per hour).
In light of the gap that existed between the research realities of requiring very high dosages of intravenously administered arginine and the low dosages found being used among many products in the marketplace, this motivated the MuscleMeds research team to explore new, effective ways of increasing NO levels in the bloodstream. The research team literally reviewed thousands of molecules and research studies in search of discovering a new, more effective way to increase NO levels in the bloodstream. This massive research effort culminated in the development of the new class of Nitric Oxide Super-Molecule contained in eNOXIDE.
Nitric Oxide research studies to determine the best way for boosting
NO levels. After extensive review, MuscleMeds scientists discovered that the NO precursor and NO stimulating products were at best minimally effective in elevating NO in the bloodstream, with individual effectiveness results varying. A plethora of research indicates the dose-response limitations of using orally administered arginine or other arginine based compounds, such as Arginine, Arginine Alpha-Ketoglutarate (AAKG), Citrulline and other NO precursors and stimulators. For example, when reviewing the research conducted using arginine, it was found that in order to achieve some elevation of NO, very large dosages of arginine were required, using intravenous administration. Even more problematic, the research reveals that the oral dosage methods used by all supplements (capsules, tablets, powder mixes, liquid drinks, etc.) were much less effective compared to intravenous (I.V.) administration.
Other efficacy concerns related to using NO precursors and NO stimulators include the widespread practice of products containing low, ineffective dosages. For example, a typical effective dosage reported in the medical research report is 30 grams of arginine, administered intravenously (I.V.) all within 30 minutes. Compare this to the low,
sub-optimum dosing common among most NO supplements, where
3 grams or less of Arginine or AAKG is administered. To make matters worse, in an effort to prolong the NO elevations many of these products make the mistake of using a 6-hour sustained release tablets. Sustaining a sub-optimal 3 gram dose over a 6-hour period translates into delivering an even more ineffective sub-optimal dosage of a mere
0.5 grams per hour. Moreover, factor in that oral arginine is estimated to be about 70% bioavailable by some experts, and your dosage becomes even more dismal and sub-optimal (0.35 grams per hour).
In light of the gap that existed between the research realities of requiring very high dosages of intravenously administered arginine and the low dosages found being used among many products in the marketplace, this motivated the MuscleMeds research team to explore new, effective ways of increasing NO levels in the bloodstream. The research team literally reviewed thousands of molecules and research studies in search of discovering a new, more effective way to increase NO levels in the bloodstream. This massive research effort culminated in the development of the new class of Nitric Oxide Super-Molecule contained in eNOXIDE.
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